RSL3 [1219810-16-8]

MedChem Express

RSL3 [1219810-16-8]

10

1219810-16-8

98.1%

C23H21ClN2O5

440.88

RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells.

O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC

2°C to 8°C,-20°C,-80°C

12352200