Rucaparib [283173-50-2]

MedChem Express

Rucaparib [283173-50-2]

10

283173-50-2

99.27%

C19H18FN3O

323.36

Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research.

FC1=CC2=C3C(CCNC2=O)=C(C4=CC=C(CNC)C=C4)NC3=C1

2°C to 8°C,-20°C,-80°C

12352200