Ruxolitinib Phosphate [1092939-17-7]
S5243
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameRuxolitinib Phosphate [1092939-17-7]
- Delivery Days Customer9
- CertificationResearch Use Only
- Scientific DescriptionRuxolitinib Phosphate (INCB018424, INC424) is the phosphate salt form of Ruxolitinib. Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays, >130-fold selectivity for JAK1/2 versus JAK3. Ruxolitinib kills tumor cells through toxic mitophagy. Ruxolitinib induces autophagy and enhances apoptosis.
- UNSPSC12352200