S-Ruxolitinib (INCB018424) [941685-37-6]

Selleck Chemicals

S-Ruxolitinib (INCB018424) [941685-37-6]

9

Research Use Only

S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. Phase 3.

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