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Salubrinal [405060-95-9]

Research Use Only
HY-15486
MedChem Express
CAS Number405060-95-9
Product group Chemicals
Estimated Purity99.5%
Molecular Weight479.81
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Salubrinal [405060-95-9]
  • Delivery Days Customer
    10
  • CAS Number
    405060-95-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.5%
  • Molecular Formula
    C21H17Cl3N4OS
  • Molecular Weight
    479.81
  • Scientific Description
    Salubrinal is a cell-permeable and selective inhibitor of eIF2alpha dephosphorylation. Salubrinal acts as a dual-specificity phosphatase 2 (Dusp2) inhibitor and suppresses inflammation in anti-collagen antibody-induced arthritis. Salubrinal has antiviral activity against HSV-1 and inhibits dephosphorylation of eIF2alpha mediated by the HSV-1 protein ICP34.5.
  • SMILES
    O=C(NC(NC(NC1=CC=CC2=C1N=CC=C2)=S)C(Cl)(Cl)Cl)/C=C/C3=CC=CC=C3.[(E)]
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200