Voxtalisib [934493-76-2]

MedChem Express

Voxtalisib [934493-76-2]

10

934493-76-2

Research Use Only

98.68%

C13H14N6O

270.29

Voxtalisib (XL765) is a potent PI3K inhibitor, which has a similar activity toward class I PI3K (IC50s=39, 113, 9 and 43 nM for p110alpha, p110beta, p110gamma and p110delta, respectively), also inhibits DNA-PK (IC50=150 nM) and mTOR (IC50=157 nM). Voxtalisib (XL765) inhibits mTORC1 and mTORC2 with IC50s of 160 and 910 nM, respectively.

O=C1C(C2=NNC=C2)=CC3=C(C)N=C(N)N=C3N1CC

2°C to 8°C,-20°C,-80°C

12352200