SAR405838 [1303607-60-4]

MedChem Express

SAR405838 [1303607-60-4]

10

1303607-60-4

Research Use Only

95%

C29H34Cl2FN3O3

562.5

SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.

O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)N[C@@H]5CC[C@@H](O)CC5

-20°C,-80°C

12352200