Savolitinib [1313725-88-0]

MedChem Express

Savolitinib [1313725-88-0]

10

1313725-88-0

Research Use Only

98.45%

C17H15N9

345.36

Savolitinib (AZD-6094) is a potent, highly selective, and orally bioavailable c-Met inhibitor with IC50 s of 5 nM and 3 nM for c-Met and p-Met, respectively. Savolitinib (AZD-6094) selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. Antineoplastic activity.

CN1N=CC(C2=CN=C3C(N([C@H](C4=CN5C(C=C4)=NC=C5)C)N=N3)=N2)=C1

2°C to 8°C,-20°C,-80°C

12352200