SB 242084 dihydrochloride [1049747-87-6]
HY-13409A
CAS Number1049747-87-6
Product group Chemicals
Estimated Purity98.33%
Molecular Weight467.78
Overview
- SupplierMedChem Express
- Product NameSB 242084 dihydrochloride [1049747-87-6]
- Delivery Days Customer10
- CAS Number1049747-87-6
- Estimated Purity98.33%
- Molecular FormulaC21H21Cl3N4O2
- Molecular Weight467.78
- Scientific DescriptionSB 242084 dihydrochloride is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier). SB 242084 dihydrochloride increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 dihydrochloride also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 dihydrochloride has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage.
- SMILESO=C(N1CCC2=C1C=C(Cl)C(C)=C2)NC3=CC=C(OC4=CC=CN=C4C)N=C3.[H]Cl.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200