SB 271046 Hydrochloride [209481-24-3]

MedChem Express

SB 271046 Hydrochloride [209481-24-3]

10

209481-24-3

Research Use Only

98.64%

C20H23Cl2N3O3S2

488.45

SB 271046 Hydrochloride (SB 271046A) is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 microM).

ClC1=CC2=C(C=C1)SC(S(=O)(NC3=CC=C(C(N4CCNCC4)=C3)OC)=O)=C2C.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200