Scutellarin [27740-01-8]

MedChem Express

Scutellarin [27740-01-8]

10

27740-01-8

98%

C21H18O12

462.36

Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-kappaB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC50s of 26 microM, 253 microM and 136 microM, respectively.

O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3C(O)=O)=C4O)C2=C4O

2°C to 8°C,-20°C,-80°C

12352200