Semagacestat [425386-60-3]
HY-10009
CAS Number425386-60-3
Product group Chemicals
Estimated Purity95.06%
Molecular Weight361.44
Overview
- SupplierMedChem Express
- Product NameSemagacestat [425386-60-3]
- Delivery Days Customer10
- CAS Number425386-60-3
- CertificationResearch Use Only
- Estimated Purity95.06%
- Molecular FormulaC19H27N3O4
- Molecular Weight361.44
- Scientific DescriptionSemagacestat is a gamma-secretase inhibitor, inhibits beta-amyloid (Abeta42), Abeta38 and Abeta40 with IC50s of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC50 of 14.1 nM. Semagacestat can be used for the research of alzheimers disease.
- SMILESO=C([C@H]1NC([C@@H](NC([C@H](C(C)C)O)=O)C)=O)N(CCC2=C1C=CC=C2)C
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200