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Senicapoc [289656-45-7]

Research Use Only
HY-50694
MedChem Express
CAS Number289656-45-7
Product group Chemicals
Estimated Purity99.66%
Molecular Weight323.34
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Senicapoc [289656-45-7]
  • Delivery Days Customer
    10
  • CAS Number
    289656-45-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.66%
  • Molecular Formula
    C20H15F2NO
  • Molecular Weight
    323.34
  • Scientific Description
    Senicapoc (ICA-17043) is a potent and selective Gardos channel (Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.
  • SMILES
    O=C(C(C1=CC=CC=C1)(C2=CC=C(C=C2)F)C3=CC=C(F)C=C3)N
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200