Setipiprant [866460-33-5]

MedChem Express

Setipiprant [866460-33-5]

10

866460-33-5

Research Use Only

98.7%

C24H19FN2O3

402.42

Setipiprant (ACT-129968) is an orally active and selective CRTH2 antagonist. Setipiprant interacts with hCRTH2 receptor with an IC50 value of 6 nM. Setipiprant inhibits prostanoid receptors hDP1 and hEP2 with IC50 values of 1290 and 2600 nM, respectively. Setipiprant can be used for the research of asthma and rhinitis.

O=C(O)CN1C2=C(CN(C(C3=C4C=CC=CC4=CC=C3)=O)CC2)C5=C1C=CC(F)=C5

2°C to 8°C,-20°C,-80°C

12352200