SGC-CBP30 [1613695-14-9]

MedChem Express

SGC-CBP30 [1613695-14-9]

10

1613695-14-9

Research Use Only

99.06%

C28H33ClN4O3

509.04

SGC-CBP30 is a potent and highly selective CBP/p300 bromodomain (Kds of 21 nM and 32 nM for CBP and p300, respectively) inhibitor, displaying 40-fold selectivity over the first bromodomain of BRD4 [BRD4(1)] bound. SGC-CBP30 strongly reduces secretion of IL-17A in Th17 cells and has anti-inflammatory effects.

C[C@H](N1CCOCC1)CN2C(CCC3=CC=C(OC)C(Cl)=C3)=NC4=CC(C5=C(C)ON=C5C)=CC=C42

2°C to 8°C,-20°C,-80°C

12352200