SNS-032 (BMS-387032) [345627-80-7]

Selleck Chemicals

SNS-032 (BMS-387032) [345627-80-7]

9

345627-80-7

Research Use Only

SNS-032 (BMS-387032) has firstly been described as a selective inhibitor of CDK2 with IC50 of 48 nM in cell-free assays and is 10- and 20-fold selective over CDK1/CDK4. It is also found to be sensitive to CDK7/9 with IC50 of 62 nM/4 nM, with little effect on CDK6. SNS-032 (BMS-387032) induces apoptosis. Phase 1.

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