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Sorafenib (BAY 43-9006) [284461-73-0]

Research Use Only
S7397
Selleck Chemicals
CAS Number284461-73-0
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Sorafenib (BAY 43-9006) [284461-73-0]
  • Delivery Days Customer
    9
  • CAS Number
    284461-73-0
  • Certification
    Research Use Only
  • Scientific Description
    Sorafenib (BAY 43-9006, NSC-724772) is a multikinase inhibitor of Raf-1 and B-Raf with IC50 of 6 nM and 22 nM in cell-free assays, respectively. Sorafenib inhibits VEGFR-2, VEGFR-3, PDGFR-bèta, Flt-3 and c-KIT with IC50 of 90 nM, 20 nM, 57 nM, 59 nM and 68 nM, respectively. Sorafenib induces autophagy and apoptosis and activates ferroptosis with anti-tumor activity.
  • UNSPSC
    12352200