Spironolactone [52-01-7]

MedChem Express

Spironolactone [52-01-7]

10

52-01-7

Research Use Only

99.58%

C24H32O4S

416.57

Spironolactone (SC9420) is an orally active aldosterone mineralocorticoid receptor antagonist with an IC50 of 24 nM. Spironolactone is also a potent antagonist of androgen receptor with an IC50 of 77 nM. Spironolactone promotes autophagy in podocytes.

C[C@@]12[C@](OC3=O)(CC3)CC[C@@]1([H])[C@@]([C@@H](CC4=CC5=O)SC(C)=O)([H])[C@]([C@]4(CC5)C)([H])CC2

2°C to 8°C,-20°C,-80°C

12352200