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Sunitinib (SU11248) [557795-19-4]

Research Use Only
S7781
Selleck Chemicals
CAS Number557795-19-4
Product group Chemicals
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Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Sunitinib (SU11248) [557795-19-4]
  • Delivery Days Customer
    9
  • CAS Number
    557795-19-4
  • Certification
    Research Use Only
  • Scientific Description
    Sunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRbèta with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1alfa. Sunitinib induces autophagy and apoptosis.
  • UNSPSC
    12352200