Sunitinib (SU11248) malate [341031-54-7]
S1042
Overview
- SupplierSelleck Chemicals
- Product NameSunitinib (SU11248) malate [341031-54-7]
- Delivery Days Customer9
- CAS Number341031-54-7
- CertificationResearch Use Only
- Scientific DescriptionSunitinib (SU11248) malate is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRbèta with IC50 of 80 nM and 2 nM in cell-free assays, and also inhibits c-Kit. Sunitinib Malate effectively inhibits autophosphorylation of Ire1alfa. Sunitinib Malate increases both death receptor and mitochondrial-dependent apoptosis.
- UNSPSC12352200