T-5224 [530141-72-1]

MedChem Express

T-5224 [530141-72-1]

10

530141-72-1

Research Use Only

98.01%

C29H27NO8

517.53

T-5224 is a transcription factor c-Fos/activator protein (AP)-1 inhibitor with anti-inflammatory effects, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. T-5224 inhibits the IL-1beta-induced up-regulation of Mmp-3, Mmp-13 and Adamts-5 transcription.

OC1=NOC2=CC(COC3=C(CCC(O)=O)C=C(C(C4=C(O)C=C(OC5CCCC5)C=C4)=O)C=C3)=CC=C21

2°C to 8°C,-20°C,-80°C

12352200