Bio-Connect

TAK-960 dihydrochloride

HY-15160B
MedChem Express
Estimated Purity99.19%
Product group Chemicals
Molecular Weight634.52
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TAK-960 dihydrochloride
  • Delivery Days Customer
    10
  • Estimated Purity
    99.19%
  • Molecular Formula
    C27H36Cl2F3N7O3
  • Molecular Weight
    634.52
  • Scientific Description
    TAK-960 dihydrochloride is an orally available, selective inhibitor of polo-like kinase 1 (PLK1), with an IC50 of 0.8 nM. TAK-960 dihydrochloride also shows inhibitory activities against PLK2 and PLK3, with IC50s of 16.9 and 50.2 nM, respectively. TAK-960 dihydrochloride inhibits proliferation of multiple cancer cell lines and exhibits significant efficacy against multiple tumor xenografts.
  • SMILES
    [H]Cl.O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(N4C)C(N(C5CCCC5)CC(F)(F)C4=O)=N3)C=C2F.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200