Talnetant [174636-32-9]

MedChem Express

Talnetant [174636-32-9]

10

174636-32-9

Research Use Only

99.15%

C25H22N2O2

382.45

Talnetant (SB 223412) is a selective, competitive, brain-permeable NK3 receptor antagonist with a Ki of 1.4 nM in hNK-3-CHO cells. Talnetant is 100-fold more selective for hNK-3 relative to the hNK-2 receptor and has no affinity for hNK-1. Talnetant can be used in schizophrenia-related studies.

OC1=C(C(N[C@H](C2=CC=CC=C2)CC)=O)C3=C(N=C1C4=CC=CC=C4)C=CC=C3

2°C to 8°C,-20°C,-80°C

12352200