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Taltobulin trifluoroacetate [228266-41-9]

Research Use Only
HY-15584A
MedChem Express
CAS Number228266-41-9
Product group Chemicals
Estimated Purity99.96%
Molecular Weight587.67
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Taltobulin trifluoroacetate [228266-41-9]
  • Delivery Days Customer
    10
  • CAS Number
    228266-41-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.96%
  • Molecular Formula
    C29H44F3N3O6
  • Molecular Weight
    587.67
  • Scientific Description
    Taltobulin trifluoroacetate (HTI-286 trifluoroacetate), a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo. Taltobulin trifluoroacetate inhibits the polymerization of purified tubulin, disrupts microtubule organization in cells, and induces mitotic arrest, as well as apoptosis.
  • SMILES
    CC(C)(C)[C@H](NC([C@H](C(C)(C1=CC=CC=C1)C)NC)=O)C(N([C@@H](C(C)C)/C=C(C(O)=O)\C)C)=O.O=C(O)C(F)(F)F
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200