Tamoxifen [10540-29-1]
HY-13757A
Overview
- SupplierMedChem Express
- Product NameTamoxifen [10540-29-1]
- Delivery Days Customer10
- CAS Number10540-29-1
- CertificationResearch Use Only
- Estimated Purity98.89%
- Molecular FormulaC26H29NO
- Molecular Weight371.51
- Scientific DescriptionTamoxifen (ICI 47699) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 microM and 1.8 microM, respectively. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse.
- SMILESCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200