Tenovin-6 Hydrochloride [1011301-29-3]

MedChem Express

Tenovin-6 Hydrochloride [1011301-29-3]

10

1011301-29-3

Research Use Only

98%

C25H35ClN4O2S

491.09

Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 microM, 10 microM, and 67 microM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH).

O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2.Cl

2°C to 8°C,-20°C,-80°C

12352200