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TG 100801 [867331-82-6]

Research Use Only
HY-10186
MedChem Express
CAS Number867331-82-6
Product group Chemicals
Estimated Purity95%
Molecular Weight580.08
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TG 100801 [867331-82-6]
  • Delivery Days Customer
    10
  • CAS Number
    867331-82-6
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C33H30ClN5O3
  • Molecular Weight
    580.08
  • Scientific Description
    TG 100801 is a proagent that generates TG 100572 by de-esterification in development to treat age-related macular degeneration. TG 100572 is a multi-targeted kinase inhibitor which inhibits receptor tyrosine kinases and Src kinases; has IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1, 0.4, 1, 0.2 for VEGFR1, VEGFR2, FGFR1, FGFR2, PDGFRbeta, Fgr, Fyn, Hck, Lck, Lyn, Src, Yes, respectively.
  • SMILES
    O=C(C1=CC=CC=C1)OC2=CC=C(Cl)C(C3=CC(C)=C(N=C(NC(C=C4)=CC=C4OCCN5CCCC5)N=N6)C6=C3)=C2
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200