Umbralisib hydrochloride [1532533-78-0]
HY-12279C
CAS Number1532533-78-0
Product group Chemicals
Estimated Purity98.98%
Molecular Weight608.01
Overview
- SupplierMedChem Express
- Product NameUmbralisib hydrochloride [1532533-78-0]
- Delivery Days Customer10
- CAS Number1532533-78-0
- Estimated Purity98.98%
- Molecular FormulaC31H25ClF3N5O3
- Molecular Weight608.01
- Scientific DescriptionUmbralisib (TGR-1202) hydrochloride is an orally active, potent and selective dual PI3Kdelta and casein kinase-1-epsilon (CK1epsilon) inhibitor, with EC50 of 22.2 nM and 6.0 microM, respectively. Umbralisib hydrochloride exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib hydrochloride can be used for haematological malignancies reseach.
- SMILESO=C1C(C2=CC=CC(F)=C2)=C([C@@H](N3N=C(C4=CC=C(OC(C)C)C(F)=C4)C5=C(N)N=CN=C53)C)OC6=CC=C(F)C=C16.[H]Cl
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200