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TH287 [1609960-30-6]

Research Use Only
HY-16965
MedChem Express
CAS Number1609960-30-6
Product group Chemicals
Estimated Purity98.14%
Molecular Weight269.13
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TH287 [1609960-30-6]
  • Delivery Days Customer
    10
  • CAS Number
    1609960-30-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.14%
  • Molecular Formula
    C11H10Cl2N4
  • Molecular Weight
    269.13
  • Scientific Description
    TH287 is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 microM. TH287 could act as a chemotherapeutic agent for cancer research.
  • SMILES
    NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC)=N1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200