Thalidomide 4-fluoride [835616-60-9]

MedChem Express

Thalidomide 4-fluoride [835616-60-9]

10

835616-60-9

Research Use Only

95%

C13H9FN2O4

276.22

Thalidomide 4-fluoride (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1 (HY-129966).

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3F)=O

2°C to 8°C,-20°C,-80°C

12352200