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Thalidomide [50-35-1]

Research Use Only
HY-14658
MedChem Express
CAS Number50-35-1
Product group Chemicals
Estimated Purity99.81%
Molecular Weight258.23
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Thalidomide [50-35-1]
  • Delivery Days Customer
    10
  • CAS Number
    50-35-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.81%
  • Molecular Formula
    C13H10N2O4
  • Molecular Weight
    258.23
  • Scientific Description
    Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a Kd of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.
  • SMILES
    O=C1N(C2CCC(NC2=O)=O)C(C3=CC=CC=C31)=O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200