Tivozanib [475108-18-0]
HY-10977
CAS Number475108-18-0
Product group Chemicals
Estimated Purity99.37%
Molecular Weight454.86
Overview
- SupplierMedChem Express
- Product NameTivozanib [475108-18-0]
- Delivery Days Customer10
- CAS Number475108-18-0
- CertificationResearch Use Only
- Estimated Purity99.37%
- Molecular FormulaC22H19ClN4O5
- Molecular Weight454.86
- Scientific DescriptionTivozanib (AV-951; KRN951) is a selective and orally active VEGFR tyrosine kinase inhibitor with IC50 of 0.21, 0.16, 0.24 nM for VEGFR-1, VEGFR-2, VEGFR-3, respectively. Tivozanib inhibits angiogenesis and vascular permeability in tumor tissues and shows antitumor activity. Tivozanib has the potential for the research of metastatic renal cell carcinoma (RCC) .
- SMILESO=C(NC1=CC=C(C=C1Cl)OC2=CC=NC3=CC(OC)=C(C=C23)OC)NC4=NOC(C)=C4
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200