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Tizoxanide [173903-47-4]

Research Use Only
HY-12687
MedChem Express
CAS Number173903-47-4
Product group Chemicals
Estimated Purity98.1%
Molecular Weight265.25
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tizoxanide [173903-47-4]
  • Delivery Days Customer
    10
  • CAS Number
    173903-47-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.1%
  • Molecular Formula
    C10H7N3O4S
  • Molecular Weight
    265.25
  • Scientific Description
    Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46microM and 0.15 microM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-kappaB and the MAPK signaling pathways in LPS-treated macrophage cells.
  • SMILES
    O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200