TMPA [1258275-73-8]
HY-18555
CAS Number1258275-73-8
Product group Chemicals
Estimated Purity98.22%
Molecular Weight380.48
Overview
- SupplierMedChem Express
- Product NameTMPA [1258275-73-8]
- Delivery Days Customer10
- CAS Number1258275-73-8
- Estimated Purity98.22%
- Molecular FormulaC21H32O6
- Molecular Weight380.48
- Scientific DescriptionTMPA is a high-affinity Nur77 antagonist that binds to Nur77 leading to the release and shuttling of LKB1 in the cytoplasm to activate AMPKalpha. TMPA effectively lowers blood glucose and attenuates insulin resistance in type II db/db, high-fat diet and streptozotocin-induced diabetic mice. TMPA reduces RICD (restimulation-induced cell death) in human T cells, can also be used in studies of cancer and T-cell apoptosis dysregulation.
- SMILESCOC1=C(CC(OCC)=O)C(C(CCCCCCC)=O)=CC(OC)=C1OC
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200