TMS [24144-92-1]

MedChem Express

TMS [24144-92-1]

10

24144-92-1

99.21%

C18H20O4

300.35

TMS ((E)-2,3,4,5-tetramethoxystilbene) is a selective and competitive CYP1B1 inhibitor with an IC50 of 6 nM and a Ki value of 3 nM. TMS shows a lesser extent inhibitory effect on CYP1A1 (IC50=300 nM) and CYP1A2 (IC50=3.1 microM). TMS is a methylated derivative of resveratrol and has anti-cancer activity.

COC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2)C(OC)=C1

2°C to 8°C,-20°C,-80°C

12352200