Trametinib (GSK1120212) [871700-17-3]

Selleck Chemicals

Trametinib (GSK1120212) [871700-17-3]

9

Research Use Only

Trametinib (GSK1120212, JTP-74057, Mekinist) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. Trametinib activates autophagy and induces apoptosis.

12352200