Trimetazidine dihydrochloride [13171-25-0]

MedChem Express

Trimetazidine dihydrochloride [13171-25-0]

10

13171-25-0

Research Use Only

99.94%

C14H24Cl2N2O3

339.26

Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit beta-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective agent, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor.

COC1=CC=C(CN2CCNCC2)C(OC)=C1OC.[H]Cl.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200