Bio-Connect

Trimetrexate [52128-35-5]

HY-10373
MedChem Express
CAS Number52128-35-5
Product group Chemicals
Estimated Purity98.63%
Molecular Weight369.42
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Trimetrexate [52128-35-5]
  • Delivery Days Customer
    10
  • CAS Number
    52128-35-5
  • Estimated Purity
    98.63%
  • Molecular Formula
    C19H23N5O3
  • Molecular Weight
    369.42
  • Scientific Description
    Trimetrexate (CI-898) is an antibiotic, also a potent and orally active dihydrofolate reductase (DHFR) inhibitor, reducing the production of DNA and RNA precursors and leading to cell death, with IC50 values of 4.74 nM and 1.35 nM for human DHFR and Toxoplasma gondii DHFR. Trimetrexate can also inhibit the growth of various cancer cells. Trimetrexate can be used for researching Pneumocystis carinii pneumonia (PCP) and cancer.
  • SMILES
    NC1=C(C(C)=C2CNC3=CC(OC)=C(OC)C(OC)=C3)C(C=C2)=NC(N)=N1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200