Trimipramine maleate [521-78-8]

MedChem Express

Trimipramine maleate [521-78-8]

10

521-78-8

99.97%

C24H30N2O4

410.51

Trimipramine maleate is a 5-HT receptor antagonist, with pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine maleate is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 microM, 2.11 microM, 3.72 microM, 8.00 microM, respectively. Trimipramine maleate has vascular activity and anxiolytic efficacy.

CC(CN(C)C)CN1C2=C(C=CC=C2)CCC3=C1C=CC=C3.O=C(O)/C=C\C(O)=O

2°C to 8°C,-20°C,-80°C

12352200