Tucidinostat [1616493-44-7]

MedChem Express

Tucidinostat [1616493-44-7]

10

1616493-44-7

98.41%

C22H19FN4O2

390.41

Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10) inhibitor, with IC50s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 (IC50s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9.

O=C(C1=CC=C(CNC(/C=C/C2=CN=CC=C2)=O)C=C1)NC(C=CC(F)=C3)=C3N

2°C to 8°C,-20°C,-80°C

12352200