Deucravacitinib [1609392-27-9]
HY-117287
CAS Number1609392-27-9
Product group Chemicals
Estimated Purity98.44%
Molecular Weight425.46
Overview
- SupplierMedChem Express
- Product NameDeucravacitinib [1609392-27-9]
- Delivery Days Customer10
- CAS Number1609392-27-9
- Estimated Purity98.44%
- Molecular FormulaC20H19D3N8O3
- Molecular Weight425.46
- Scientific DescriptionDeucravacitinib (BMS-986165) is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases, which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain. Deucravacitinib inhibits IL-12/23 and type I IFN pathways. Deucravacitinib, the FDAs world first de novo deuterium, is available for study in moderate to severe plaque psoriasis.
- SMILESO=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=CC=CC(C4=NN(C)C=N4)=C3OC)NC([2H])([2H])[2H]
- Storage Instruction-20°C,-80°C
- UNSPSC12352200