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Ulixertinib [869886-67-9]

Research Use Only
HY-15816
MedChem Express
CAS Number869886-67-9
Product group Chemicals
Estimated Purity99.49%
Molecular Weight433.33
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ulixertinib [869886-67-9]
  • Delivery Days Customer
    10
  • CAS Number
    869886-67-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.49%
  • Molecular Formula
    C21H22Cl2N4O2
  • Molecular Weight
    433.33
  • Scientific Description
    Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.
  • SMILES
    O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200