UMI-77 [518303-20-3]
HY-18628
Overview
- SupplierMedChem Express
- Product NameUMI-77 [518303-20-3]
- Delivery Days Customer10
- CAS Number518303-20-3
- CertificationResearch Use Only
- Estimated Purity95%
- Molecular FormulaC18H14BrNO5S2
- Molecular Weight468.34
- Scientific DescriptionUMI-77 is a selective Mcl-1 inhibitor, which shows high binding affinity to Mcl-1 (IC50=0.31 microM). UMI-77 binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.
- SMILESO=C(O)CSC1=CC(NS(=O)(C2=CC=C(Br)C=C2)=O)=C3C=CC=CC3=C1O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200