UNC0321 [1238673-32-9]

MedChem Express

UNC0321 [1238673-32-9]

10

1238673-32-9

98%

C27H45N7O3

515.69

UNC0321 is a potent and selective histone methyltransferase G9a inhibitor with a Ki of 63 pM and with assay-dependent IC50 values of 6-9 nM. UNC0321 also inhibits GLP with assay-dependent IC50 values of 15-23 nM. UNC0321 has anti-apoptotic activity and has potential application in diabetic vascular complications.

CN1CCC(NC2=C3C=C(OC)C(OCCOCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1

2°C to 8°C,-20°C,-80°C

12352200