UNC0379 TFA [1620401-83-3]

MedChem Express

UNC0379 TFA [1620401-83-3]

10

1620401-83-3

99.46%

C25H36F3N5O4

527.58

UNC0379 TFA is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 microM, KD value of 18.3 microM. UNC0379 TFA can be used in the research of inflammation and cancers, such as pulmonary fibrosis, ovarian cancer, neuroblastoma.

COC1=C(OC)C=C2C(N=C(N3CCCC3)N=C2NCCCCCN4CCCC4)=C1.O=C(O)C(F)(F)F

2°C to 8°C,-20°C,-80°C

12352200