Upadacitinib [1310726-60-3]

MedChem Express

Upadacitinib [1310726-60-3]

10

1310726-60-3

98.56%

C17H19F3N6O

380.37

Upadacitinib (ABT-494) is a potent, orally active and selective Janus kinase 1 (JAK1) inhibitor (IC50=43 nM). Upadacitinib (ABT-494) displays approximately 74 fold selective for JAK1 over JAK2 (200 nM) in cellular assays dependent on specific, relevant cytokines. Upadacitinib (ABT-494) can be used for several autoimmune disorders research.

O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F

2°C to 8°C,-20°C,-80°C

12352200