URMC-099 [1229582-33-5]
S7343
Overview
- SupplierSelleck Chemicals
- Product NameURMC-099 [1229582-33-5]
- Delivery Days Customer9
- CAS Number1229582-33-5
- CertificationResearch Use Only
- Scientific DescriptionURMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.
- UNSPSC12352200