Vandetanib [443913-73-3]

MedChem Express

Vandetanib [443913-73-3]

10

443913-73-3

Research Use Only

95%

C22H24BrFN4O2

475.35

Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM).

FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C)=C(C=C23)OC

2°C to 8°C,-20°C,-80°C

12352200