Varenicline [249296-44-4]

MedChem Express

Varenicline [249296-44-4]

10

249296-44-4

Research Use Only

99.98%

C13H13N3

211.26

Varenicline (CP 526555) is a potent partial agonist for alpha4beta2 nicotinic acetylcholine receptor (nAChR) with an EC50 value of 2.3 microM. Varenicline is a full agonist for alpha3beta4 and alpha7 nAChRs with EC50 values of 55 microM and 18 microM, respectively. Varenicline is a nicotinic ligand based on the structure of cytosine, and has the potential for smoking cessation treatment.

C12=C(C=C3N=CC=NC3=C2)C4CC1CNC4

2°C to 8°C,-20°C,-80°C

12352200