Vercirnon [698394-73-9]
HY-15724
CAS Number698394-73-9
Product group Chemicals
Estimated Purity98.19%
Molecular Weight444.93
Overview
- SupplierMedChem Express
- Product NameVercirnon [698394-73-9]
- Delivery Days Customer10
- CAS Number698394-73-9
- CertificationResearch Use Only
- Estimated Purity98.19%
- Molecular FormulaC22H21ClN2O4S
- Molecular Weight444.93
- Scientific DescriptionVercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 microM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively.
- SMILESO=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(Cl)C=C2C(C3=CC=[N+]([O-])C=C3)=O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200